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單細胞測序技術服務 靶向lncRNA单细胞全转录组测序 單細胞全轉錄組測序 |
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生物分子凝聚體研究 HyPro靶RNA临近标记技术 |
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RNA-蛋白相互作用 HyPro - MS CHIRP – MS RNA pull-down MS |
RNA-RNA/DNA相互作用 HyPro-seq/芯片 CHIRP-seq |
蛋白-RNA相互作用 AGO APP seq/芯片 RIP-RNA seq/芯片 |
蛋白-蛋白相互作用 RIME MS CoIP-MS |
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NGS测序技术服务 R-loop 测序分析服务 |
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NGS测序技术服务 環狀DNA测序 |
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基因芯片技術服務 Small RNA修饰芯片 m6A单碱基分辨率芯片 mRNA&lncRNA表观转录组芯片 circRNA表观转录组芯片 |
NGS测序技术服务 表觀轉錄組學測序服務 RNA m6A甲基化测序（MeRIP Seq） |
LC-MS mRNA碱基修饰检测 tRNA碱基修饰检测 |
PCR技术服务 MeRIP-PCR技术服务 m6A绝对定量RT-PCR技术服务 m6A单碱基位点PCR（MazF酶切法）技术服务 |
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Ribo-seq Ribo seq |
核糖體-新生肽链复合物(RNC) RNC联合 circRNA芯片 RNC联合 lncRNA芯片 RNC联合mRNA-seq |
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蛋白表達定量 Label free非标定量技术 TMT标记定量技术 PRM靶向定量 |
Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia. Nat Genet. 2011
CRL4B Catalyzes H2AK119 Monoubiquitination and Coordinates with PRC2 to Promote Tumorigenesis. Cancer Cell. 2012
Hypoxia Inducible Factor 2 Alpha Inhibits Hepatocellular Carcinoma Growth Through the Transcription Factor Dimerization Partner 3/ E2F Transcription Factor 1–Dependent Apoptotic Pathway. HEPATOLOGY. 2013
Menin promotes hepatocellular carcinogenesis and epigenetically up-regulates Yap1 transcription. PNAS. 2013
Prognostic significance of 2-hydroxyglutarate levels in acute myeloid leukemia in China. PNAS. 2013
The N-terminus of histone H3 is required for de novo DNA methylation in chromatin. Proc Natl Acad Sci USA. 2009
cAMP response element-binding protein promotes gliomagenesis by modulating the expression of oncogenic microRNA-23a. PNAS. 2012
Quantitative detection of multiple gene promoter hypermethylation in tumor tissue, serum, and cerebrospinal fluid predicts prognosis of malignant gliomas. Neuro Oncol. 2010
Potential Tumor Suppressor NESG1 as an Unfavorable Prognosis Factor in Nasopharyngeal Carcinoma. PLoS One. 2011
MiR-185 Targets the DNA Methyltransferases 1 and Regulates Global DNA Methylation in human glioma. Molecular Cancer. 2011
Silencing of RASSF3 by DNA Hypermethylation Is Associated with Tumorigenesis in Somatotroph Adenomas. PLoS One. 2013
Genome-wide DNA methylation patterns in IVF-conceived mice and their progeny: A putative model for ART-conceived humans. Reprod Toxicol. 2011
Genome-wide analysis of histone H3 lysine 27 trimethylation by ChIP-chip in gastric cancer patients. J Gastroenterol. 2009
Genome-wide analysis of histone H3 lysine 4 trimethylation in peripheral blood mononuclear cells of minimal change nephrotic syndrome patients. Am J Nephrol. 2009
Genome-wide analysis of HMGA2 transcription factor binding sites by ChIP on chip in gastric carcinoma cells. Mol Cell Biochem. 2012
125I seed irradiation induces up-regulation of the genes associated with apoptosis and cell cycle arrest and inhibits growth of gastric cancer xenografts. Journal of Experimental & Clinical Cancer Research. 2012
Effects of DNMT1 silencing on malignant phenotype and methylated gene expression in cervical cancer cells. Journal of Experimental & Clinical Cancer Research. 2012
